Known as the Great Hurricane of 1780, it is among the deadliest storms ever recorded. The hurricane strengthened and grew in size as it tracked slowly westward, first affecting Barbados, the western most Caribbean island, late on 9 October. In October 1780, a powerful storm slammed the islands of the Caribbean, killing more than 20,000 people. More than 20,000 people were killed as the storm swept through the eastern Caribbean Sea, with the greatest loss of life centred on the … Although specifics on this hurricane’s track and strength are unknown, forecasters and historians believe that the Great Hurricane of 1780 initially formed near the Cape Verde Islands on October 9, 1780. Great hurricane of 1780, hurricane (tropical cyclone) of October 1780, one of the deadliest on record in the Atlantic Ocean. The Great Hurricane of 1780, also known as Huracán San Calixto, the Great Hurricane of the Antilles, and the 1780 Disaster, [1] [2] is the deadliest Atlantic hurricane on record. Between 22,000 and 27,501 people died throughout the Lesser Antilles when the storm passed through them from October 10–16.